Lemborexant Shift Work Treatment Study

Inclusion Criteria: * Full-time night shift work (at least 6 hours per shift, 4 days per week or 32 hours per week) * Employed as a night shift worker for at least 3 months * Self-reported concerns about daytime sleepiness and difficulty sleeping during the daytime Exclusion Criteria: * Pregnancy (verified by urine pregnancy test) or plan to become pregnant in the next 3 months * Currently breastfeeding * Inadequate opportunity for sleep during the daytime (\< 7 hours opportunity) after overnight shift * Extreme circadian preference (based on Horne \& Ostberg Morningness-Eveningness Questionnaire) * Severe depressive symptoms (\>25 on CES-D) * Unwillingness to discontinue sleep aids (prescription or non-prescription) during the study period * Presence of sleep disordered breathing (verified by Apnea link) * Self-reported diagnosis of narcolepsy, restless legs syndrome * Self-reported intake of \>600mg of caffeine per night shift or use of stimulants during night shift, rotational, or irregular shifts * Unstable or untreated medical or psychiatric condition based on clinical interview. * Severe hepatic or renal impairment (based on chemistry panel); * Self-reported use of digoxin or strong or moderate cytochrome P450 3A4 isozyme inhibitors or cytochrome P450 3A4 isozyme inducers for 6 months prior to or during the study