UnknownPhase 1

Contextual Interference, Engagement , and Change in Motor Performance in Stroke

Israel50 participantsStarted 2020-01-01

Plain-language summary

The aim of the study is to examine associations between contextual interference (CI), engagement during practice and changes in upper limb motor performance among patients post-stroke. Fifty patients over the age of 18, after a stroke, in the sub-acute and early chronic stages who have weakness of the upper extremity and are treated in a rehabilitation center will be recruited. The study will include participation in five sessions: session 1 for baseline assessment, session 2-4 for practice of upper extremity functions, and session 5 for post intervention assessment. The intervention will include training of three items from the Wolf motor function test in random order (high CI group) or block order (low CI group). Outcomes of engagement will include the brain engagement index, heart rate variability and galvanic skin response. Outcomes of learning will include the pre-post change in performance of the wolf motor function selected items.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Five days to 1-year post-stroke * Score of 11-60 on the Fugl-Meyer Assessment for upper extremity * The patient receives physical therapy and/or occupational therapy rehabilitation treatment Exclusion Criteria: * A history of neurological diseases other than stroke or orthopedics conditions that impair upper extremity function * Pain that prevents active movement of the upper extremity * Hemodynamic instability * Cognitive decline and language difficulties that do not allow understanding of instructions and cooperation.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Brain Engagement Index

Timeframe: Practice session 1 (1-2 days following pre-intervention session), practice session 2 (1-2 days following practice session1), and practice session 3 (1-2 days following practice session1)

Change in time to complete each of three items of the Wolf Motor Function Test (WMFT)

Timeframe: Pre-intervention session (first session), post-intervention session (session 5, 5-7 days following the pre-intervention session))

Trial details

NCT IDNCT05342688

SponsorUniversity of Haifa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-01

Contact for this trial

Michal Kafri, PhD

972586862261 kafri.michal@gmail.com

View on ClinicalTrials.gov More Hemiparesis;Poststroke/CVA trials