The population in Taiwan is rapidly aging with an increasing proportion of older persons who experience cognitive difficulties but are otherwise physically healthy. As such there is a critical and urgent need for effective interventions to enhance older adult cognitive health. This present sub-project is part of the larger integrated project that will address this need by conducting cognitive training interventions on community older adults using the National Taiwan Science Education Center (NTSEC) as the public engagement window and collecting research behavioral and neurophysiological data to empirically and objectively examine intervention efficacies. In this sub-project, the investigators implement a clinical trial to evaluate an open-ended, flexible cognitive training intervention in middle to older adults aged 50 yrs or above using a 12-week Lego Robot Programming (Lego RP) protocol developed in the investigators' lab at the Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University. The Lego RP training requires participants to generate and update abstract mental hypotheses of the effect of program codes on the physical actions of a robot based on how the robot behaves. Such mental processing is thought to drive flexible coordination between neural processes in the brain and benefit a broad range of cognitive abilities in older adults. The investigators target to obtain pre- and post-intervention behavioral and neurophysiological data (including brain imaging indicators) in 40 experimental participants, 40 active control participants, and 40 passive control participants over a period of 3 years.
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Changes of neural functional activity during inferential processing
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Changes of overall accuracy during inferential processing
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Changes of learning rate during inferential processing
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Changes of strategic performance during inferential processing
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Changes in the Montreal Cognitive Assessment (MoCA) score
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Change in Wechsler Memory Scale III Logical Memory I & II
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Change in Wechsler Memory Scale III Face Memory
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Change in Wechsler Memory Scale III Verbal Paired Memory
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Change in Wechsler Memory Scale III Family Pictures I & II
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Change in Wechsler Memory Scale III Word Lists I & II
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Change in Wechsler Memory Scale III Visual Reproduction I & II
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Change in Wechsler Memory Scale III Spatial Span
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Change in Wechsler Memory Scale III Digit Span
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Change in Wechsler Adult Intelligence Scale III Vocabulary
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Change in Wechsler Adult Intelligence Scale III Digit Symbol
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Change in Wechsler Adult Intelligence Scale III Block Design
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Change in Wechsler Adult Intelligence Scale III Arithmetic
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Change in Wechsler Adult Intelligence Scale III Matrix Reasoning
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