UnknownNot Applicable

Treatment of Intraosseous Periodontal Defects With Amelogenins

Italy22 participantsStarted 2023-02-01

Plain-language summary

The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of amelogenins, compared to MINSD alone. A total of 22 patients will be enrolled, selected by inclusion and exclusion criteria and randomly divided in two groups: amelogenin (A) and no-amelogenin group (B).

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients diagnosed with periodontitis; * Age ≥ 18 years old; * Presence of at least 10 teeth per arch; * Presence of at least two teeth with Probing Depth (PD) ≥ 5 mm per quadrant; * Presence of at least one intraosseous pocket; * Single-rooted and multi-rooted teeth. Exclusion Criteria: * Patients with systemic diseases; * Prolonged antibiotic or anti-inflammatory treatment within 4 weeks prior to periodontal therapy; * Pregnant or lactating; * Tobacco smokers (≥ 10 cigarettes per day); * Multi-rooted teeth with furcation involvement; * Third molars.

What they're measuring

Change of Clinical Attachment Level (CAL) gain (millimeters)

Timeframe: baseline and 6 months after periodontal therapy

Trial details

NCT IDNCT05315804

SponsorFederico II University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-01

Contact for this trial

Luca Ramaglia

+393476912911 luca.ramaglia@unina.it

View on ClinicalTrials.gov More Periodontal Bone Loss trials