Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients (NCT05311852) | Clinical Trial Compass
CompletedNot Applicable
Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients
Italy34 participantsStarted 2021-08-16
Plain-language summary
The study explore the efficacy of PEA-LUT in patients suffering from neurological symptoms of Long-Covid
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* previous diagnosis of SARS-CoV-2 infection confirmed through detection of virus RNA by polymerase chain reaction (PCR) testing of a nasopharyngeal swab;
* subsequent recovery from infection as defined by two consecutive negative PCR tests separated by at least a day;
* mild form of COVID-19 (symptoms may include fever, cough, sore throat, malaise, myalgia, anorexia, nausea, diarrhoea, anosmia and ageusia) without necessitating hospital admission;
* complaints of cognitive difficulties and/or sense of fatigue, persisting after SARS-CoV-2 infection.
Exclusion Criteria:
* prior or concurrent diagnosis of neurological, psychiatric, endocrine, metabolic or cardiopulmonary conditions;
* clinical and/or radiological evidence of COVID-19 related pneumonia during the active phase of the disease;
* anaemia;
* current pharmacological treatment with corticosteroids, antihistamines, antihypertensives, diuretics, antidepressants, anxiolytic or hypnotic drugs at the time of study
What they're measuring
1
changes in % of test amplitude in LICI 100
Timeframe: LICI 100 was assessed two times, at enrollment and after 8 weeks of treatment duration
Trial details
NCT IDNCT05311852
SponsorDepartment of Neurorehabilitation, Hospital of Vipiteno-Sterzing (BZ) Italy