CompletedNot Applicable

Sugars in Cigarettes

United States30 participantsStarted 2022-02-24

Plain-language summary

The aim of this study is to investigate the impact of sugar levels in cigarette tobacco on cigarette abuse liability and appeal. Participants will attend several clinic visits to smoke cigarettes with different levels of sugars and will complete multiple questionnaires to assess their experiences. Each of the sessions will be separated by at least 48 hours but not more than 5 days. The hypothesis is that the measures collected in this study will indicate lower abuse liability for cigarettes with lowest sugar content.

Who can participate

Age range21 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female age 21 years or older * Smoking cigarettes that have been evaluated to have medium levels of sugar content * No quit attempts in the past month nor intentions to quit smoking in the next month * Participants are in good physical health (no unstable medical conditions) as determined by the licensed medical professional * Participants are in stable, good mental health (e.g. not currently, within the past 6 months, experiencing unstable or untreated psychiatric diagnosis) as determined by the licensed medical professional * Stable vitals sign measurements (systolic BP ≤ 160 and \>90 mmHg, diastolic BP ≤ 100 and \>50 mmHg and heart rate ≤105 and \> 45 bpm) as determined by the licensed medical professional * Participants must be able to read for comprehension or completion of study documents (confirmed during informed consent process) * Participants have provided written informed consent to participate in the study. Exclusion Criteria: * Significant immune system disorders, respiratory diseases, kidney or liver diseases or any other medical disorders that may affect biomarker data as determined by the licensed medical professional * Women who are pregnant or nursing or planning to become pregnant.

What they're measuring

Impact of Cigarette Sugar Content on Product Satisfaction.

Timeframe: At each session, 2 hours post all puffs (assessed at all 4 sessions, each session was up to 4 hours, and all sessions took place between 2-3 weeks post enrollment, separated by 2-5 days)

Impact of Sugar Content on Behavioral Outcomes Using the Multiple Choice Procedure Task.

Timeframe: At each session, 2 hours post all puffs (assessed at all 4 sessions, each session was up to 4 hours, and all sessions took place between 2-3 weeks post enrollment, separated by 2-5 days)

Trial details

NCT IDNCT05308316

SponsorMasonic Cancer Center, University of Minnesota

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-10-13

Results submitted2025-07-28

View on ClinicalTrials.gov More Tobacco Use trials

Plain-language summary

Who can participate

Age range21 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Impact of Cigarette Sugar Content on Product Satisfaction.

Timeframe: At each session, 2 hours post all puffs (assessed at all 4 sessions, each session was up to 4 hours, and all sessions took place between 2-3 weeks post enrollment, separated by 2-5 days)

Impact of Sugar Content on Behavioral Outcomes Using the Multiple Choice Procedure Task.

Timeframe: At each session, 2 hours post all puffs (assessed at all 4 sessions, each session was up to 4 hours, and all sessions took place between 2-3 weeks post enrollment, separated by 2-5 days)