Cytokine Expression in Psoriasis Patients with and Without Joint Involvement

Inclusion criteria: * For psoriasis patients : * Age over 18 years old * Signed informed consent * 5 year old psoriasis at least * At least one skin lesion over 2 cm * Without any articular symptoms * Without any DMARDs * Without anticoagulant treatments or coagulation disease * With normal articular and enthesis sonography * For psoriatic arthritis patients : * Age over 18 years old * Signed informed consent * Psoriatic arthritis according to CASPAR criteria * Without any DMARDs * Without anticoagulant treatments or coagulation disease * With at least one synovitis at inclusion * For controls * Age and sex matched with a patient without any rheumatic or dermatologic medical conditions * No treatment with corticosteroïds or non-steroïdial anti-inflammatory drugsAge over 18 years old Exclusion criteria: ▪ For psoriasis patients : * Joint damage according to CASPAR criteria * Echography activity in favor of chronic inflammatory rheumatism * For patients and controls: * Without social protection rights * People under judiciary protection, of less than 18 years old, pregnant woman, breast feeding women, jailed patients.