Laser Therapy for Treatment of Genitourinary Syndrome of Menopause (GSM) in Postmenopausal Women

Inclusion Criteria: * Women of any age with established menopause of 5 years or more who report genitourinary discomfort, dyspareunia, sequelae, genital atrophy, voiding discomfort, voiding urgency or urinary incontinence. Postmenopausal status is defined if patients have at least 12 continuous months of amenorrhea for no other apparent reason or permanently elevated follicle-stimulating hormone (FSH) blood levels (≥30 mIU/mL). * Patients who have had cancer treatment already completed and in the process of remission. * Sexually active * Nulliparous or who have had vaginal deliveries or caesarean section * That they do not receive hormone replacement therapy in any of its routes of administration. If you received HRT, 4 months must have elapsed since stopping treatment before starting the trial protocol. * Motivated and committed to complete the trial Exclusion Criteria: * According to the pelvic organ prolapse quantification system \[POP-Q\], POP\>Stage 2, , severe urinary or fecal incontinence (FI) or any disease that could influence the study protocol. In addition, patients will be advised to refrain from vaginal practices for three days prior to each biopsy (one at the beginning and one at the end of treatment). * Women who are not sexually active, do not have coital relationships, either with a partner or alone * Women with recurrent cystitis or candidiasis * Women with little motivation to participate in the trial * Minors * Patients who do not have the ability to co…