This is a 16-week, multicenter, randomized, parallel-group, double-blind, controlled study. After assessing eligibility during a screening period of up to 30 days, approximately 320 subjects at least 18 years old who are diagnosed with moderate to severe papulopustular rosacea will be randomized in a 3:3:2 ratio to DFD-29 (40 mg), Doxycycline capsules 40 mg, or Placebo once daily for 16 weeks.
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Investigator's Global Assessment (IGA) Treatment Success Compared to Placebo.
Timeframe: Baseline to Week 16.
Change in Total Inflammatory Lesion Count Compared to Placebo.
Timeframe: Baseline to Week 16.