The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.
Who can participate
Age range18 Years – 45 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of SCD (HbSS, HbSC (Hemoglobin Sickle C Disease), HbS-beta-0 thalassemia, and HbS-beta+ thalassemia) or report of SCT (SCD is Hgb electrophoresis confirmed; SCT evaluated by SickleScan);
* Able and intends to conceive a child in the next 2 years (first child or another child);
* Speaks and reads English;
* 18 to 45 years;
* At-risk for having a child with SCD (i.e., sexual/ reproductive partner has SCD, SCT, or unknown sickle cell status); and
* Wants to avoid the risk of a child with SCD.
* The age range is based on typical reproductive age for SCD where median survival is 42 years for men and 48 years for women.
Exclusion Criteria:
* Legally blind;
* Physically unable to complete the study questionnaires or the intervention;
* Report health history of hysterectomy, tubal ligation, medically or surgically induced menopause, or vasectomy that would
* Prevent ability to bear children;
* Report a desire to remain childless or have no further children;
* Report knowing or being a relative or friend of a participant previously enrolled in the study, or
* Previous participation in a CHOICES study.