CompletedNot Applicable

18F-PBR06/Total Body PET Imaging in Patients With STEMI

China26 participantsStarted 2022-07-08

Plain-language summary

The study will use 18F-PBR06/uExplorer to study the activation of macrophages and systemic perfusion in patients with ST-segment elevation myocardial infarction (STEMI) or stable angina (SA). Participants will receive the total-body PET/CT scan on the seventh day (Day 7, D7) and D180 of enrolment.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18-75 years old * Diagnosed with STEMI, NSTEMI or suspected SA (ACC/AHA guidelines) * Half male and half female * Undergo CAG and PCI treatment if necessary (primary PCI for STEMI patients within12 hours after symptom onset) * Written informed consents will be offered and signed by all participants Exclusion Criteria: * History of myocardial infarction/vascular disease/heart failure/systemic inflammatory diseases before enrolment * Patients who are pregnant/breastfeeding, or in a plan to have a baby during the year after CAG/PCI * People under the age of 18 years old * Inability to lie or maintain posture during the scanning procedure

What they're measuring

Change from baseline TSPO uptake (SUV max) at 6 month

Timeframe: Day 7 and Day 180 after enrolment

Change from baseline Blood flow value (ml/g/min) at 6 month

Timeframe: Day 7 and Day 180 after enrolment

Trial details

NCT IDNCT05269446

SponsorRenJi Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-05-31

View on ClinicalTrials.gov More Myocardial Infarction trials