Evaluation of Four New Ready to Drink Oral Nutritional Supplements: Adult ONS Trial

Inclusion Criteria: * Male or female * ≥16 years of age * Identified as being malnourished/at risk of malnutrition by malnutrition screening tools \[i.e., MUST score ≥1, and/or using or requiring ONS at least once daily as part of nutritional management plan\] * Expected to receive at least one bottle of ONS per day * Written or electronic informed consent from patient, or verbally given consent countersigned by a witness for those physically unable to sign Exclusion Criteria: * Patients receiving parenteral nutrition or ≥70% total energy requirements from enteral tube feeding * Patients with major hepatic dysfunction (i.e., decompensated liver disease) * Patients with major renal dysfunction \[i.e., requiring filtration or stage 4/5 chronic kidney disease (CKD)\] * Cancer patients likely to anticipate significant gastrointestinal disturbances/taste changes as a result of Systemic Anti-Cancer Therapy (SACT) * Patients with active/chronic gastrointestinal disease or impaired gastrointestinal function * Patients with significant dysphagia/high aspiration risk * Participation in other clinical intervention studies within 1 month of this study * Adults lacking mental capacity to consent * Allergy to any study product ingredients * Investigator concern regarding ability or willingness of patient to comply with the study requirements.