ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery (NCT05257941) | Clinical Trial Compass
TerminatedPhase 1/2
ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery
Stopped: study specific patients are now scheduled at another hospital for this procedure
United States116 participantsStarted 2022-01-27
Plain-language summary
This study is being done to compare 2 types of pain control methods and determine which is more effective postoperatively for laparoscopic colorectal surgery. Group 1 will receive an intrathecal (IT) injection in the back in which a small dose duramorph and bupivacaine will be placed into the spinal fluid. Group 2 will receive an erector spinae plane (ESP) block in which bupivacaine and decadron are injected near the nerves under a muscle in the back.
Who can participate
Age range18 Years ā 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients undergoing an elective laparoscopic colorectal procedure at Indiana University Hospital or Methodist Hospital
* ASA Class 1, 2, 3 (American Society of Anesthesiologists physical status classification system)
* Age 18 to 80 years (male or female)
* BMI \< 40kg/m2
* Desires regional anesthesia for postoperative pain control
Exclusion Criteria:
* Any contraindication for neuraxial analgesia or ESP block procedure
* Contraindications for neuraxial analgesia include: Elevated intracranial pressure (except in cases of pseudo-tumor cerebri), infection at the site of injection, lack of consent from the patient, patient refusal, true allergy to any drug used in the spine, and uncorrected hypovolemia.
* Contraindications for ESP block procedure include: Infection at the site of injection, patient refusal, true allergy to any of the drugs used in the block, and lack of patient consent.
* Any patient undergoing a laparoscopic abdominoperineal resection.
* Any physical, mental or medical conditions which, in the opinion of the investigators, may confound quantifying postoperative pain resulting from surgery.
* Known true allergy to the study medications (morphine, bupivacaine, decadron, Tylenol, Celebrex)
* Takes over 30 mg of oral morphine equivalents daily
* Any history of substance abuse in the past 6 months
* End stage liver disease, end stage renal disease
* Body weight of \< 50 kg