Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil

Inclusion Criteria: * Patient age 18-75 years * Patient has a related donor who is at least Human Leukocyte Antigen (HLA) haploidentical, or an unrelated donor who is a most a single HLA antigen mismatch. * Patient signs the Informed Consent Form for the study * Patient has a hematologic malignancy other than myelofibrosis and meets standard criteria for allogeneic stem cell transplant. * Patient is deemed suitable to receive Fludarabine and Total Body Irradiation (Flu/TBI) 1125 or Flu/TBI 800 conditioning regimen as standard of care transplant * Donor is willing to donate peripheral blood stem cells Exclusion Criteria: * Patient has a diagnosis of myelofibrosis * Patient has high titer antibodies against one or more donor HLA antigens * Patient has undergone prior autologous or allogeneic stem cell transplant. * Inability to collect sufficient peripheral blood stem cells from the donor