The central hypothesis of this study is that the addition of dupilumab treatment onto standard-of-care intranasal corticosteroids will improve patient-reported measures of disease activity and sense of smell in a cohort of mostly ethnical and racial minority patients with CRSwNP
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Change in Sinonasal outcome test (SNOT-22) score, scale 0-110, higher is worse outcome
Timeframe: at 2, 16, 36, and 52 weeks of treatment
Change in University of Pennsylvania Smell Identification Test (UPSIT) scores, scale 0-40, lower is worse outcome values
Timeframe: at 2, 16, 36, and 52 weeks of treatment
Change in nasal peak flow (NPF) value (L/min)
Timeframe: at 2, 16, 36, and 52 weeks of treatment