SuspendedNot Applicable

Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure

Stopped: Study temporarily paused.

United States50 participantsStarted 2022-08-30

Plain-language summary

This is a prospective cohort study for 50 patients admitted to the cardiac care unit requiring clinically-indicated diuretic therapy for congestive heart failure. The purpose of this study is to assess the role of non-invasive cardiac output monitoring (NICOM) with the Starling Fluid Management System (Baxter Medical, Deerfield, IL) in determining volume status in patients with acute decompensated heart failure requiring intravenous diuretic therapy.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Diagnosis of congestive acute decompensated heart failure (preserved or reduced ejection fraction) requiring clinically indicated IV diuresis
✓. Admission to coronary/cardiac intensive care unit or cardiac step down unit
✓. Able to provide written informed consent
✓. Anticipated need for IV diuretics \> 24 hrs

Exclusion criteria

✕. Prisoner, pregnancy or post-partum stage, or age \< 18 years
✕. Known allergy to sensory material or gel
✕. End stage renal disease or need for CRRT
✕. Inability or contraindication to do a passive leg raise with both extremities (i.e., balloon pump, impella, spinal injury, amputation)
✕. Other situation that might increase subject risk, interfere with study procedures, or confound study findings based on the opinion of the clinician/investigator

What they're measuring

Percent Change in Stroke Volume Index (SVI) after passive leg raise (PLR)

Timeframe: Baseline, At Discharge (up to 1 week)

Trial details

NCT IDNCT05240651

SponsorNYU Langone Health

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-07-01

View on ClinicalTrials.gov More Acute Decompensated Heart Failure trials