Exercise in Older Adults at Risk for Type 2 Diabetes (NCT05229705) | Clinical Trial Compass
CompletedNot Applicable
Exercise in Older Adults at Risk for Type 2 Diabetes
Canada60 participantsStarted 2022-09-23
Plain-language summary
Older adults with type 2 diabetes experience neurocognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (i.e., those who are overweight and/or prediabetic) are at higher risk for neurocognitive decline, and intervening at this point may prevent or delay the onset of such decline. One promising lifestyle intervention that has been shown to improve cognitive function and brain health in other populations is resistance exercise. We previously conducted a 6-month resistance training randomized controlled trial (RCT) pilot study that showed a large scale trial would be viable and feasible. Consequently, we would like to explore resistance exercise as a lifestyle intervention to improve cognition and brain structure in older adults at risk for diabetes.
Who can participate
Age range60 Years – 80 Years
SexALL
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Inclusion criteria
✓. Community-dwelling
✓. Aged 60-80 years
✓. "At-risk" for diabetes, where they have one of the following: i) blood glucose level of 6.1-7 mmol/L, ii) body mass index \> 25, or iii) score \> 21 on the CANRISK diabetes questionnaire
✓. Score \> 24/30 on MMSE
✓. Score \> 6/8 on the IADL scale
✓. Visual acuity of at least 20/40, with or without corrective lenses
✓. Speak and understand English fluently
✓. Complete the PAR-Q
Exclusion criteria
✕. Current medical condition for which exercise is contraindicated
✕. Participated regularly in resistance or aerobic training in the last 6 months