Exercise in Older Adults at Risk for Type 2 Diabetes (NCT05229705) | Clinical Trial Compass
CompletedNot Applicable
Exercise in Older Adults at Risk for Type 2 Diabetes
Canada60 participantsStarted 2022-09-23
Plain-language summary
Older adults with type 2 diabetes experience neurocognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (i.e., those who are overweight and/or prediabetic) are at higher risk for neurocognitive decline, and intervening at this point may prevent or delay the onset of such decline. One promising lifestyle intervention that has been shown to improve cognitive function and brain health in other populations is resistance exercise. We previously conducted a 6-month resistance training randomized controlled trial (RCT) pilot study that showed a large scale trial would be viable and feasible. Consequently, we would like to explore resistance exercise as a lifestyle intervention to improve cognition and brain structure in older adults at risk for diabetes.
Who can participate
Age range
60 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Community-dwelling
. Aged 60-80 years
. "At-risk" for diabetes, where they have one of the following: i) blood glucose level of 6.1-7 mmol/L, ii) body mass index \> 25, or iii) score \> 21 on the CANRISK diabetes questionnaire
. Score \> 24/30 on MMSE
. Score \> 6/8 on the IADL scale
. Visual acuity of at least 20/40, with or without corrective lenses
. Speak and understand English fluently
. Complete the PAR-Q
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.