Active — Not RecruitingNot Applicable

Moving Well for Total Knee Arthroplasty (TKA)

United States79 participantsStarted 2022-04-05

Plain-language summary

The purpose of this study is to assess the efficacy of a behavioral intervention, Moving Well, in improving levels of anxiety and depression for patients undergoing total knee arthroplasty (TKA).

Who can participate

Age range

50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects must have their primary TKR (one knee or both knees) scheduled in 8 weeks or more * Be willing to participate in the Moving Well (intervention) arm or Staying Well (attention control) arm * Are willing to work with a coach * ≥ 50 years of age * Speak English * Have access to the internet, computer, and a working phone * We will prioritize the recruitment of subjects with low socioeconomic status defined as being a beneficiary of Medicaid or no insurance and an underrepresented racial/ethnic group (Hispanic/Black). Exclusion Criteria: * Non-English speakers * The intervention will first be delivered in English to ensure feasibility with the content before adapting the material for patients who speak other languages. * TKR was a result of a septic joint or revision (implant malfunction) * Unable to exercise (e.g., bed bound or wheelchair bound) * Have had contralateral TKR or other joint replacement surgery (hip, shoulder) within the past 5 years * If they have RA or other connective tissue disease: Lupus, ankylosing spondylitis, psoriatic arthritis, scleroderma, infectious arthritis, polymyalgia rheumatica.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in level of anxiety from baseline using the Generalized Anxiety Disorder Assessment (GAD-7)

Timeframe: Baseline, 6 months post-surgery

Change in level of depression from baseline using the Patient Health Questionnaire-8 (PHQ-8)

Timeframe: Baseline, 6 months post-surgery

Trial details

NCT IDNCT05217420

SponsorWeill Medical College of Cornell University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06

View on ClinicalTrials.gov More Osteoarthritis, Knee trials

Who can participate

Age range

50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.