This study will primarily evaluate the pharmacokinetics of satralizumab in pediatric patients aged 2-11 years with anti-aquaporin-4 (AQP4) antibody seropositive neuromyelitis optica spectrum disorder (NMOSD). Efficacy, safety, tolerability, and pharmacodynamics will be evaluated in a descriptive manner, given the small number of patients who will be enrolled in this study.
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Summary of observed serum concentration [Cthrough] of satralizumab
Timeframe: Week 48
Apparent clearance [CL/F] of satralizumab
Timeframe: Week 48
Apparent volume of distribution [V/F] of satralizumab
Timeframe: Week 48
Area under the concentration-time curve [AUC] of satralizumab
Timeframe: Week 48
Reference Study ID Number: WN41733 https://forpatients.roche.com/