CompletedNot Applicable

Letrozole in Induction of Abortion of Anembryonic Pregnancy

Egypt96 participantsStarted 2022-04-03

Plain-language summary

Some studies suggest the prescription of aromatase inhibitors prior to the use of misoprostol for inducing drug abortion. the aim of the study is to compare the effectiveness of various regimens of letrozole combined with misoprostol versus using misoprostol alone in inducing complete abortion in patients with blighted ovum.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * first trimester of pregnancy * pregnancy duration less than 12 weeks based on LMP. * non-viable fetus (blighted ovum) Exclusion Criteria: * No heart disease, * No asthma * No History of thromboembolism * No History of cancer * No renal failure * No liver diseases * History of allergy to misoprostol or letrozole drugs.

What they're measuring

Complete abortion

Timeframe: 2 days

Trial details

NCT IDNCT05198050

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09-30

View on ClinicalTrials.gov More Anembryonic Pregnancy trials