Stopped: Closed per SRC Low Accrual Policy
This phase I/II trial studies the side effects of bomedemstat and maintenance immunotherapy with atezolizumab and to see how well they work in treating patients with newly diagnosed extensive stage small cell lung cancer. Bomedemstat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving bomedemstat and atezolizumab may work better in treating patients with extensive stage small cell lung cancer.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Number of Participants Experiencing a Dose Limiting Toxicity (DLT)
Timeframe: Up to 21 days from initiation of treatment
Progression Free Survival
Timeframe: From the date of study enrollment up to 2 years
Incidence Patients Experiencing Adverse Events
Timeframe: From initial of treatment, up to 30 days after discontinuation of study treatment, up to 7 months