Conversion Therapy of Fruquintinib in Combination With Sintilimab and SOX in Unresectable Gastric Cancer

Inclusion criteria

• ✓. Absolute Neutrophil Count (ANC) ≥1.5×109/L, White Blood Cell≥3.5×109/L;
• ✓. Platelet Count of ≥100×109/L;
• ✓. Hemoglobin≥90g/L;
• ✓. Total Bilirubin (TBIL) ≤1.5 x ULN;
• ✓. ALT and AST\<2.5 x ULN, GPT≤1.5×ULN; If there is liver metastasis, then ALT and AST\<5.0 x ULN, GPT≤3.0×ULN;
• ✓. Serum Creatinine (SCr) ≤1.0×ULN;
• ✓. Endogenous creatinine clearance rate \> 60ml / min (Cockcroft Gault formula);