"Surgical Vs. Non-surgical Peri-implant Therapy"

To take part in this study, patients must present at least one implant diagnosed with peri-implantitis \[i.e., peri-implant bone level ≥ 3mm apical to the most coronal portion of the intraosseous part of the implant, peri-implant pocket depth (PPD) ≥ 6 mm, and presence of bleeding and/or suppuration on gentle probing (BOP/SOP) (Berglunh et al. 2018) Inclusion Criteria: * Men and women over 18 years old. * Presence of ≥ 1 endosseous implants with clinical and radiographic signs of peri- implantitis \[i.e., peri-implant bone level ≥ 3mm apical to the most coronal portion of the intraosseous part of the implant, PPD ≥ 6 mm, and presence of bleeding and/or suppuration on gentle probing (BOP/SOP). * Implant function time ≥ 1 year. * Vertical peri-implant bone defect (defects of 2-3 walls and a defect depth ≥ 3 mm). * Presence of at least 2 mm of keratinized mucosa. * Absence of active periodontal disease. * Good level of oral hygiene (Plaque Index \< 25%) (O'Leary et al. 1972) * Screw-retained single-unit crowns and partial dental prosthesis that allowed correct access for brushing; and, if not, * Prostheses that could be modified. * Absence of occlusal overload. Exclusion Criteria: * Clinical implant mobility. * Radiographic peri-implant bone loss \> 50%. * Pregnancy or lactating females. * Any medical condition which contraindicated surgical peri-implant therapy. * Previous non-surgical treatment (i.e., subgingival debridement) of the affected implants at least 12 months bef…