This study will test whether 42 days of cannabis abstinence, compared to continued cannabis use, is associated with improvements in cognition and psychiatric disorder symptoms. Identical twins, who are concordant on cannabis use, will be experimentally-manipulated to be discordant for 42 days. Each twin, within a twin pair, will be randomly assigned to either the contingency management condition, incentive-based protocol to promote cannabis abstinence, or control condition, no changes in cannabis use requested.
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Change in attention performance
Timeframe: Change from baseline to day 42
Change in episodic memory
Timeframe: Change from baseline to day 42
Change in working memory
Timeframe: Change from baseline to day 42
Change in receptive vocabulary
Timeframe: Change from baseline to day 42
Change in reading decoding
Timeframe: Change from baseline to day 42
Change in immediate memory/verbal learning
Timeframe: Change from baseline to day 4
Change in pattern comparison processing speed
Timeframe: Change from baseline to day 42
Change in oral symbol digit test processing speed
Timeframe: Change from baseline to day 42
Change in attention and executive function
Timeframe: Change from baseline to day 42