Effectiveness of the Decolonization Circuit of S. Aureus, Reducing Infection in Primary Arthropla… (NCT05158322) | Clinical Trial Compass
CompletedNot Applicable
Effectiveness of the Decolonization Circuit of S. Aureus, Reducing Infection in Primary Arthroplasty of the Lower Limb
Spain90 participantsStarted 2021-10-14
Plain-language summary
Lower limb joint replacement surgery is one of the most prevalent globally. In our center, more than 400 lower limb arthroplasties (LLA) are performed annually. Developing a Surgical Site Infection (SSI) after (LLA) increases morbidity, mortality and healthcare costs. Staphylococcus aureus is the main causative agent of SSI and especially in LLA. One third of the population is a nasal carrier of Staphylococcus aureus, being a risk factor for patients who have to undergo knee replacement or hip replacement. Several studies have confirmed that the detection of S. aureus carriers and their subsequent decolonization reduces SSI rates
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Over 18 years old
* Patients who are going to undergo knee or hip replacement surgery.
* Patients with a positive result in the first nasal smear to S. aureus, and follow the decolonization protocol.
* Patients who give their informed consent to participate in the study.
Exclusion Criteria:
* Patients scheduled for VPE less than 2 days after surgery.
* Patients unable to give their informed consent freely. Inadequate cognitive ability
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial focused on decolonizing S. aureus before hip or knee replacement — was I tested for S. aureus carriage before my surgery, and does that affect my infection risk?
2The trial measured patient satisfaction with how well the decolonization process was explained to nurses — does my care team use a formal decolonization protocol, and how would they walk me through what I'd need to do at home before surgery?
3Since this trial is already completed, are the results available, and do they suggest the decolonization circuit reduced surgical site infections enough to be worth adopting as standard practice here?
4If a decolonization regimen like the one in this trial isn't already part of my pre-surgical routine, is there evidence-based reason to add it for my specific situation, or would standard infection-prevention measures be sufficient?
5How does the nurse-led education component studied in this trial compare to what I'd actually receive at this hospital, and is there anything I should be proactively asking or doing to prepare before my arthroplasty?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Evaluate with a VAS scale (0-10) the satisfaction of the participant with the information on the decolonization process of S. aureus.