The purpose of this study is to observe the safety and efficacy of Modigraf in de novo pediatric allograft liver and kidney transplantation recipients. This study will also monitor dose changes and tacrolimus whole blood trough levels of Modigraf based immunosuppression regimen.
Age range
17 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Percentage of Participants With Acute Rejection (AR)
Timeframe: From first dose to month 12
Percentage of Participants with Biopsy-Proven Acute Rejections (BPAR)
Timeframe: From first dose to month 12
Percentage of Participants with clinically suspected Rejection
Timeframe: From first dose to month 12
Number of Participants who Died
Timeframe: From first dose to month 12
Number of participants with graft failure
Timeframe: From first dose to month 12
Number of dose adjustments throughout the study period
Timeframe: From first dose to month 12
Number of participants with Treatment Emergent adverse events (AEs)
Timeframe: From first dose to month 12
Whole Blood Trough Levels of Tacrolimus
Timeframe: From month 1 through month 12 (predose)