MRB 0.3% Serum Effectiveness on 2 Early Clinical Markers of Photoinduced Cutaneous Aging: Actinic Lentigo and Actinic Keratosis

Inclusion Criteria: * Minimum of 5 actinic lentigos and 3 actinic keratoses of grade 1 or 2 on each hemi-face of the face and/or hemi-cranium (in men with baldness) * Phototype I to III * Patients with free, informed, written consent to participate in the study. * Women unable to conceive or women of childbearing potential with a negative urine pregnancy test and using contraception Exclusion Criteria: * Subjects with less than 5 actinic lentigos or less than 3 actinic keratoses of grade 1 or 2 on each hemiface of the face and/or skull (for men with baldness) * Phototype IV to VI * Immunocompromised subject * Subjects with a history of skin carcinoma in the treated areas * Subjects using another active treatment for actinic keratoses or lentigos (or having used one in the past 3 months) * Subjects unable to understand the information (due to language or psychiatric reasons) * Subjects without social insurance * Pregnant women * Breastfeeding women * Women of childbearing age without contraception * Subjects under legal protection measures * Subjects unable to express their consent * Subjects under legal protection