Saccharomyces Cerevisiae for Irritable Bowel Syndrome

Inclusion Criteria: * Male and female patients between 18 and 75 years of age, * Patients having confirmed IBS according to Rome IV criteria (newly and previously non-responder to treatment), * Pain/ discomfort score strictly above 1 and strictly below 6 as determined on a pain/ discomfort scale using arbitrary grading from 0 to 7 in 7 days preceding the inclusion visit, * Not hypersensitive to any of the ingredients of the drug. Exclusion Criteria: * Patients with an organic intestinal disease (Crohn's disease, ulcerative colitis, etc.), * Pregnant females * Treatments likely to influence IBS (anti-depressants, opioids, and narcotic analgesics) * Patients with chronic alcoholism, vegetarian or vegan regimens * Eating disorders such as anorexia or bulimia * Documented food allergies.