Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY)

Neurologically deceased donors who meet the inclusion and exclusion criteria will be eligible for participating in this study along with the correlating organ recipients who meet inclusion criteria. Donor Inclusion Criteria: * ≥18 years of age; * Neurologically deceased; * Consent for deceased organ donation; * All organ recipients have been identified; * ≥ 1 kidney allocated to a recipient. Donor Exclusion Criteria: * Known hypersensitivity to tacrolimus or polyoxyl 60 hydrogenated castor oil; * One or more organs allocated to a non-participating transplant program; * Unlikely access to study drug (e.g., due to supply issues, or pharmacist availability); * One or more organ recipients has not agreed to receive an organ from a donor participating in the study; * One or more organs are allocated to a recipient under the age of 18; * A transplant physician has judged that donor tacrolimus will be unsuitable for an intended recipient. Recipient Inclusion Criteria * Organ/Transplant graft originated from a donor enrolled in this study. No exclusion criteria.