The project focuses on perioperative bleeding that requires transfusion of blood products and supplementation of intravascular volume with crystalloids and colloids. The implemented fluid therapy affects coagulation and fibrinolysis, depending on the type of fluid used in an intravenous infusion. Massive haemorrhage significantly impacts the perioperative period and postoperative quality of life and requires individualized therapy, rending the ongoing project relevant from the perspective of the patients.
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Rotational thromboelastometry (ROTEM) viscoelastic point-of-care coagulation measurements before and after balanced crystalloid infusion
Timeframe: 60 minutes
Rotational thromboelastometry (ROTEM) viscoelastic point-of-care coagulation measurements before and after synthetic colloid infusion
Timeframe: 60 minutes
Standard laboratory tests reporting coagulation status before and after balanced crystalloid infusion
Timeframe: 60 minutes
Standard laboratory tests reporting coagulation status before and after synthetic colloid infusion
Timeframe: 60 minutes
Standard laboratory tests reporting fibrinolysis status before and after balanced crystalloid infusion
Timeframe: 60 minutes
Standard laboratory tests reporting fibrinolysis status before and after synthetic colloid infusion
Timeframe: 60 minutes