RecruitingNot Applicable

A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia

South Korea230 participantsStarted 2021-12-16

Plain-language summary

In 230 patients undergoing mastectomy, the investigators will compare opioid-free anesthesia (OFA) versus conventional opioid-based anesthesia in terms of chronic pain. The enrolled patients will be randomly assigned into two groups with 1:1 ratio. Chronic pain will be evaluated at 1 year after mastectomy based on the Breast Cancer Pain Questionnaire (BCPQ). Baseline pain sensitivity test and psychologic evaluation will be done before operation.

Who can participate

Age range19 Years – 80 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All of patients will undergo mastectomy with or without immediate breast reconstruction. Exclusion Criteria: * Previous history of breast surgery * Allergy to drug * Other cancer history * Underlying psychologic disorder * Patients with chronic pain requiring pain killers * Baseline SpO2 \<95% * Left ventricular EF \<40% * Bradycardia as HR \<50 bpm * BMI \>35kg/m2 * Pregnant woman

What they're measuring

chronic breast pain at 1 year after mastectomy

Timeframe: 1 year after mastectomy

Trial details

NCT IDNCT05146778

SponsorGangnam Severance Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-31

Contact for this trial

Sung Gwe Ahn, M.D.,Ph.D.

82220194402 asg2004@yuhs.ac

View on ClinicalTrials.gov More Breast Cancer trials