Dry eye is often reported as the most common complication after a laser refractive surgery. Any refractive procedure can lead an impact on the corneal surface and the tear film. The main cause of this dry eye is the corneal denervation caused by the destruction of the anterior stromal nerves during the ablative procedure. This loss of corneal sensitivity leads to a decrease in the blink reflex, a decrease in the secretion rate of the meibomian glands and finally an evaporated dry eye. There is also a chronic inflammation at the corneal surface that produces an increase of inflammatory cytokines and a dysfunction of the meibomian glands. Yu et al have described incidences of dry eye closed to 60% after the first month of LASIK. Hovanesian et al have observed dry eye symptoms in 50% of patients 6 months after surgery. Donnenfeld et al describe 15% of moderate dry eye in the following 3 months and 5% of severe dry eye in the first 6 months. A small number of patients will present with chronic dry eye symptoms for more than 1 year. Bower et al analyzed its incidence in 0.8% Alterations in the tear film also decrease the quality of the retinal image and produce greater number of high-order due to the irregular. Pulsed light therapy (IPL) applied preoperatively in patients who undergo a laser refractive surgery may prevent the post-surgical dry eye and improve the refractive results. The aim of our study is to evaluate the usefulness of the applied therapy for the prevention of dry eye in patients that undergo a corneal refractive procedure.
Age range
18 Years – 60 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
OSDI questionnaire
Timeframe: 0 day
Change from Baseline OSDI questionnaire
Timeframe: 7 day
Change from Baseline OSDI questionnaire
Timeframe: 30 day
Change from Baseline OSDI questionnaire
Timeframe: 90 day
Change from Baseline OSDI questionnaire
Timeframe: 180 day
Lacrimal meniscus height
Timeframe: 0 day
Change from Baseline Lacrimal meniscus height
Timeframe: 7 day
Change from Baseline Lacrimal meniscus height
Timeframe: 30 day
Change from Baseline Lacrimal meniscus height
Timeframe: 90 day
Change from Baseline Lacrimal meniscus height
Timeframe: 180 day
Tear Break-up-time
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Change from Baseline Tear Break-up-time
Timeframe: 7 day
Change from Baseline Tear Break-up-time
Timeframe: 30 day
Change from Baseline Tear Break-up-time
Timeframe: 90 day
Change from Baseline Tear Break-up-time
Timeframe: 180 day
Conjunctival and ciliary hyperemia.
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Change from Baseline Conjunctival and ciliary hyperemia.
Timeframe: 7 day
Change from Baseline Conjunctival and ciliary hyperemia.
Timeframe: 30 day
Change from Baseline Conjunctival and ciliary hyperemia.
Timeframe: 90 day
Change from Baseline Conjunctival and ciliary hyperemia.
Timeframe: 180 day
Upper and lower meibography
Timeframe: 0 day
Change from Baseline Upper and lower meibography
Timeframe: 7 day
Change from Baseline Upper and lower meibography
Timeframe: 30 day
Change from Baseline Upper and lower meibography
Timeframe: 90 day
Change from Baseline Upper and lower meibography
Timeframe: 180 day