CompletedNot Applicable

Efficacy of Platelet-Rich Plasma Versus Mesotherapy in Androgenetic Alopecia: A Retrospective Study

72 participantsStarted 2011-01-01

Plain-language summary

This is a comparative retrospective study of the efficacy of platelet-rich plasma injections and injections with commercial products advertised to promote hair regrowth for patients with androgenetic alopecia.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who underwent either PRP or mesotherapy at our dermatology clinic during 1/1/2011 and 30/12/2020 * Male patients with a clinical/ trichoscopic/ histologic diagnosis of androgenetic alopecia (stage II to V according to the Hamilton-Norwood Scale) * Female patients with a clinical/ trichoscopic/ histologic diagnosis of androgenetic alopecia (stage I to III according to Ludwig Classification) * Patients receiving no treatment or being treated for more than six months for androgenetic alopecia without change in medication. Examples of medications and interventions include, oral/topical finasteride, oral/topical minoxidil, antiandrogens, hormonal substitution, hormonal contraceptives, phototherapy/laser, cryotherapy, microneedling. * Patients who underwent trichoscopic examination and phototrichographic evaluation with our digital dermatoscope, before treatment, a month after the last injection and 3 months after treatment. * Trichoscopic photos are required to be taken from the midfrontal area and from the vertex -defined as the intersection of the line through the midsagittal line and the line passing through the external auditory canals in the coronal plane. Exclusion Criteria: * Patients with other types of alopecia, other than androgenetic alopecia * Patients with two or more diagnoses of hair loss , for example androgenetic alopecia and telogen effluvium or alopecia areata. * Patients who started concomitant medication for hair loss within s…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in hair thickness at 3 months at at 6 months from baseline

Timeframe: 0 months(baseline), 3 months (1 mont after treatment), 6 months

Change in hair density at 3 months and at 6 months from baseline

Timeframe: 0 months(baseline), 3 months (1 month after treatment), 6 months

Change in hair count at 3 months and at 6 months from baseline

Timeframe: 0 months(baseline), 3 months (1 month after treatment), 6 months

Trial details

NCT IDNCT05129800

SponsorFaculty Hospital Kralovske Vinohrady

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2020-12-30

View on ClinicalTrials.gov More Androgenetic Alopecia trials

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in hair thickness at 3 months at at 6 months from baseline

Timeframe: 0 months(baseline), 3 months (1 mont after treatment), 6 months

Change in hair density at 3 months and at 6 months from baseline

Timeframe: 0 months(baseline), 3 months (1 month after treatment), 6 months

Change in hair count at 3 months and at 6 months from baseline

Timeframe: 0 months(baseline), 3 months (1 month after treatment), 6 months