A Study to Gather Information About Rivaroxaban in Patients in the United Kingdom Who Have Cancer and Thrombosis (OSCAR-UK)

Inclusion Criteria: * Be ≥18 years of age at the time of anticoagulation initiation * Have active cancer and acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE) * Treated with rivaroxaban (or any DOAC) or LMWH as their first recorded anticoagulant prescription 7 to 30 days post-acute CAT event diagnosis * Have been active in the data set for at least 12-months prior to the index event and had at least one provider visit in the 12-months prior to the acute VTE event Exclusion Criteria: * Evidence of atrial fibrillation, recent hip/knee replacement (with 90 days of CAT), ongoing VTE treatment, valvular heart disease defined as any rheumatic heart disease, mitral stenosis or mitral valve repair/replacement * History of inferior vena cava filter before cohort entry * vitamin K antagonist (VKA) use between cohort entry and index day (initiation of DOAC or LMWH) * Evidence of any type of therapeutic anticoagulation use during all available look-back period per written prescription or patient self-report * Initiation of rivaroxaban or other DOACs or LMWH during the study period at non-therapeutic doses (e.g., enoxaparin at a dose other than 1 mg/kg twice daily or 1.5 mg/kg once daily; dalteparin at a dose other than 200 IU/kg of total body weight) * Pregnancy * Recording indicative of palliative care before cohort entry * Any clinically-relevant bleeding-related d hospitalization or VTE recurrence between the initial CAT and the start of observation