Neurological Symptoms and Findings in Individuals Exposed to Indoor Air Pollutants (NCT05111678) | Clinical Trial Compass
CompletedNot Applicable
Neurological Symptoms and Findings in Individuals Exposed to Indoor Air Pollutants
Finland35 participantsStarted 2021-04-01
Plain-language summary
To evaluate neurological findings with TSPO-PET and MRI in patients who have been exposed to indoor air pollutants and have potentially neurological symptoms.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
All:
* Signing the informed consent form
* Adults over 18 years of age
Indoor air pollutant groups:
* Exposed to indoor air pollutants
* Neurological symptoms
Neurological symptoms groups:
* Neurological symptoms possibly due to adverse external exposure
Healthy controls:
* Reported healthy person
Exclusion Criteria:
All:
* Pregnancy or breast-feeding
* Corticosteroid treatment within 4 weeks of imaging
* Patients with claustrophobia, or a history of moderate to severe anxiety disorder or panic attacks (which could potentially lead to preterm termination of the imaging)
* Contraindication to PET scan and MRI investigations
* Exposure to experimental radiation in the past 12 months such that radiodosimetry limits would be exceeded by participating in this study.
* Intolerance to previous PET scans; i.e. previous hypersensitivity reactions to any PET ligand or imaging agent or failure to participate in and comply with previous PET scans.
Neurological symptoms groups and healthy controls:
* Exposure to indoor air pollutants