Peripheral Immune System in Individuals With Schizophrenia (NCT05109065) | Clinical Trial Compass
CompletedNot Applicable
Peripheral Immune System in Individuals With Schizophrenia
United States63 participantsStarted 2021-03-01
Plain-language summary
The investigators are seeking healthy volunteers and people with schizophrenia or schizoaffective disorder for a clinical study of the immune system in psychotic disorders. This is an observational study, to understand the ways in which the immune system may be contributing to the disease process.
Who can participate
Age range18 Years – 40 Years
SexALL
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Inclusion Criteria for Subjects with schizophrenia and schizoaffective disorders:
* Schizophrenia or schizoaffective disorder diagnosis verified by interview
* Diagnosis or initiation of antipsychotic medication was within last 5 years
Inclusion Criteria for Healthy Controls:
* No known diagnosis of schizophrenia or schizoaffective disorder
* No history of depression, anxiety, bipolar disorder, PTSD, agoraphobia, panic disorder, or generalized anxiety disorder
* Negative assessment for psychotic symptoms on day of interview
Exclusion Criteria (for both groups):
* Participants have a history of bleeding disorders or are taking blood thinners.
* Participants have a history of epilepsy, known genetic disorders
* Immunocompromised state (eg., receiving immunosuppressive therapy, transplant).
* History of brain-related disease (eg., stroke)
* Any uncontrolled medical disorder such as cancer.
* History of substance abuse or positive urine toxicology screen (including test for marijuana) on the day of the blood draw