UnknownPhase 4

Extended Postoperative Oral Tranexamic Acid in Knee Replacement

United States46 participantsStarted 2021-12-07

Plain-language summary

A comparison of outcomes between use of oral tranexamic acid as compared to oral placebo in the first days after total knee replacement will be made to determine impact on clinical indications and patient reported outcomes.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Primary total knee replacement in ambulatory setting * Willing to participate * Physical therapy on site at Campbell Clinic Wolf River * Fluent in oral and written English Exclusion Criteria: * Unwilling to participate * Revision total knee replacement * Preoperative use of anticoagulants other than 81 mg aspirin * Previous history of thromboembolic event * Previous history of cancer other than non-melanoma skin cancers

What they're measuring

Hemoglobin level

Timeframe: preoperative

Hemoglobin level

Timeframe: postoperative hour 3

Hemoglobin level

Timeframe: postoperative day 3

Hemoglobin level

Timeframe: postoperative week 2

Trial details

NCT IDNCT05099276

SponsorCampbell Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

View on ClinicalTrials.gov More Knee Osteoarthritis trials