Cerebellar Stimulation for Aphasia Rehabilitation (NCT05093673) | Clinical Trial Compass
RecruitingNot Applicable
Cerebellar Stimulation for Aphasia Rehabilitation
United States60 participantsStarted 2021-10-25
Plain-language summary
The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS) boosts language therapy in helping people recover from aphasia as well as predict who is likely to respond to cerebellar tDCS.
Who can participate
Age range18 Years – 99 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Chronic ischemic or hemorrhagic left hemisphere stroke
* Fluent speaker of English by self-report
* Age 18 or older
* 6 months post onset of stroke
* Diagnosis of aphasia and naming impairment using the Western Aphasia Battery-Revised
Exclusion Criteria:
* Lesion in the right cerebellum
* Previous neurological disorder (other than stroke) affecting the brain, or any other neurodegenerative disorder or psychiatric disorder
* Seizures during the previous 6 months
* Uncorrected visual loss or hearing loss by self-report
* Use of medications that lower the seizure threshold (e.g., methylphenidate)
* Use of N-methyl-D-aspartate (NMDA) antagonists (e.g., memantine)
* History of brain surgery or any metal in the head
* Severely impaired auditory comprehension (lower than 2 on the Comprehension subscore on the Western Aphasia Battery-Revised)
* Severely limited verbal output (lower than 2 on the Spontaneous Speech rating scale on the Western Aphasia Battery-Revised)
* Individuals with severe claustrophobia, cardiac pacemakers or ferromagnetic implants, and pregnant women will be excluded from the MRI portion of the study.
What they're measuring
1
Change in accuracy of naming untrained pictures (Philadelphia Naming Test)
Timeframe: Pre-treatment to one week after the end of SFA treatment