Active — Not RecruitingNot Applicable

Effect of Physical Activity and Pain Education on Endometriosis-associated Pain

Norway83 participantsStarted 2022-02-15

Plain-language summary

Endometriosis is a benign gynecological condition where the uterine endometrium is located outside the uterus. The condition affects up to 10% of women of fertile age and up to 70% of women with endometriosis have symptoms with severe pain during menstruation (dysmenorrhea), pain during intercourse (dyspareunia), and/or chronic pelvic pain. Current treatments are dictated by the primary symptom: pain and are limited to surgery and hormonal treatments with often short-lived effects. Advances in the understanding of the condition have expanded to focus on less invasive and non-pharmacological treatments. Systematic reviews and meta-analyses of observational studies have focused on the protective role of physical activity and exercise on the risk of developing endometriosis. The results from these studies have been inconclusive. However, the efficacy of physical activity and exercise on pain among women with endometriosis has not been tested in high-quality randomized controlled trials (RCT).

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women of age 18-45 with signs of endometriosis on ultrasound and/or MRI and/or confirmed by laparoscopy with histology at Akershus University Hospital and Oslo University Hospital. Women may also be recruited through social media but must present with diagnosis of endometriosis. * genital-pelvic pain ≥4/10 as measured on a numeric rating scale. * able to understand and speak Norwegian language * able to meet at Akershus University Hospital for participation in the study * giving signed consent to participate. Exclusion Criteria: * Intra-abdominal or vaginal surgery in the last six months * Patients who have received Botox over the past four months * Severe pathology (malignancy),cardiovascular conditions and immune system diseases diagnosed by specialist; pregnancy, as well as childbirth the last 12 months and breastfeeding; severe psychiatric disorders that demands or has demanded admission to the hospital; personality disorder diagnosed by specialist and recently started or recently adjusted ongoing hormonal therapy. * Participants should not have any disease or injury that could prevent them from participating in the intervention. * Participants will be encouraged not to start with any new treatment (non-pharmacological or pharmacological) during the four-month intervention period. * Participants who have recently undergone surgery and received Botox injections into the pelvic area can be referred but must wait 4-6 months before being included in t…

What they're measuring

Endometriosis associated pain

Timeframe: Measured at baseline and after 4 months and 12 months

Trial details

NCT IDNCT05091268

SponsorUniversity Hospital, Akershus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-01