Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers

Inclusion Criteria: * Healthy males or females,18 years of age or older. * Completed written informed consent. * Female subject agrees to use an acceptable method of birth control (e.g. abstinence, condoms, hormonal birth control, IUD, tubal ligation, hysterectomy, bilateral oophorectomy, hysterectomy, post-menopausal for at least one year or male partner vasectomy). Exclusion Criteria: * Pregnancy or lactation. * A current skin disease of any type apart from mild facial acne (e.g. eczema, psoriasis) or has tattoos or excessive hair at the patch sites that would interfere with patching/skin evaluations. * Heavy alcohol consumption (i.e. more than 21 units per week or 8 units a day for men, more than 14 units per week or 4 units a day for women). * Current use or history of repeated use of street drugs. * A febrile illness lasting more than 24 hours in the six days prior to first patch application. * Significant past medical history of hepatic, renal, cardiac, pulmonary, digestive, haematological, neurological, locomotor or psychiatric disease. * Currently taking asthma medication or antihistamines for hay fever. * A history of multiple drug hypersensitivity. * Concurrent medication likely to affect the response to the test articles or confuse the results of the study (e.g. Anti-allergy, glucocorticoid, aspirin, non- steroidal anti-inflammatory, asthma or hay fever medication). * Known sensitivity to the test articles or their constituents including patch materials (for exa…