Pre-op Fluid Study (NCT05079269) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Pre-op Fluid Study
Austria550 participantsStarted 2021-11-01
Plain-language summary
Theoretical framework:
Hypotension during surgery directly impacts patients' postoperative outcomes and complications. Decrease in blood pressure measurements secondary to anesthetic drugs is an expected scenario in most surgical cases. Moreover, hypovolemia secondary to fast pre-operative period may facilitate post-induction hypotension which can be compensated by fluid bolus pre-operatively.
Who can participate
Age range45 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Scheduled for major non-cardiac surgery
✓. Having general anaesthesia
✓. Are designated ASA physical status ≥2 (ranging from mild systemic disease through severe systemic disease that is a constant threat to life)
✓. Subject to at least one of the following risk factors:
✓. Age ≥ 65 years
✓. History of peripheral arterial surgery
✓. History of coronary artery disease
✓. History of stroke or transient ischemic attack
✕. Active decompensated congestive heart failure (documented EF \< 30%)
✕. Chronic Kidney Disease (eGFR\< 30 mL/min)
✕. History of organ transplantation
What they're measuring
1
Post-induction MAP
Timeframe: 60 +/- 15 minutes before induction of anesthesia until the first 20 minutes after anesthetic induction or until surgical incision (whichever comes first)