An 18-year Follow-up Study on OSA in a Population-based Cohort (NCT05077748) | Clinical Trial Compass
CompletedNot Applicable
An 18-year Follow-up Study on OSA in a Population-based Cohort
China202 participantsStarted 2021-10-20
Plain-language summary
Our research team has established a polysomnography (PSG) quantified population-based paediatric sleep cohort in 2003 for a childhood OSA prevalence study. Subjects were recruited from 13 randomly selected primary schools. All subjects from this original cohort will be invited to join this 18-year follow-up study to repeat the following data collection: questionnaires, anthropometric measurement, sleep study, 24-hour ambulatory blood pressure (ABP) measurement, echocardiography and neurocognitive assessment.
Who can participate
Age range18 Years – 35 Years
SexALL
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Inclusion Criteria:
\- Subjects participants from the 2003 cohort
Exclusion Criteria:
* Neuromuscular disease
* Pathological central apnoea
* Severe chronic lung disease with documented hypoxaemia or awake oxygen saturation \<92%
* Chronic respiratory failure (unrelated to OSA)
* Acquired upper airway disease/obstruction
* Craniofacial abnormalities (e.g. secondary to trauma and malignancy)
Other arrangement:
* Subjects who have any respiratory illness within 2 weeks of the scheduled follow-up visit will have their assessment re-arranged until they have fully recovered.
* Subjects taking medications that may affect sleep, upper airway patency or blood pressure (for example sedatives, stimulants, antihistamines, and cough medicine) within a week from recruitment will also be rescheduled to participate when they are free from medication use for at least 2 weeks.
* Subjects with hypertension and are on anti-hypertensive therapy are allowed to continue on their medication and the information will be obtained and recorded during data collection.
What they're measuring
1
OSA status at 18-year follow-up visit
Timeframe: Through study completion, an average of 2 years