CompletedNot Applicable

Repetitive Transcranial Magnetic Stimulation to Reduce Heroin Cravings

United States24 participantsStarted 2021-10-06

Plain-language summary

The purpose of this research study is to test the effect of repetitive transcranial magnetic stimulation (rTMS) on opioid cravings among adult patients with Opioid Use Disorder.

Who can participate

Age range

18 Years – 64 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult aged 18-64, used heroin in the past 30 days; * has a history of heroin use for at least one year; * meets the clinical criteria for Opioid Use Disorder (only heroin use will be considered to meet this criteria); * meets the clinician clearance using the rTMS Patient Screening Form. Exclusion Criteria: * do not currently take and medications for a substance use disorder such as methadone, buprenorphine, naltrexone, acamprosate, disulfiram; * do not have a psychotic disorder; * do not have a diagnosis of another substance use disorder; * do not have a history of seizures or other neurological disorders including organic brain disease; epilepsy, stroke, brain lesions, multiple sclerosis, previous neurosurgery; * do not have a personal history of head trauma that resulted in a loss of consciousness for more than 5 minutes and retrograde amnesia for more than 30 minutes; * do not have a presence of non-fixed metal in body 30 cm to treatment coil. * have not taken any medication for a substance use disorder within the last 72 hours before the first rTMS treatment; * are not pregnant or think you may be pregnant.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Desires for Drug Questionnaire

Timeframe: Days 1, 3, 5, 8, 10, 12, 42

Trial details

NCT IDNCT05074524

SponsorUniversity of Nevada, Las Vegas

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-24

View on ClinicalTrials.gov More Opioid-use Disorder trials

Who can participate

Age range

18 Years – 64 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.