Abdominal Wall Reconstruction With PVDF Mesh in the Setting of Active Infection (NCT05061264) | Clinical Trial Compass
CompletedNot Applicable
Abdominal Wall Reconstruction With PVDF Mesh in the Setting of Active Infection
Brazil76 participantsStarted 2016-05
Plain-language summary
The use of synthetic mesh to repair infected defects of the abdominal wall remains controversial. This study aimed to evaluate the short-term outcomes of using PVDF mesh to treat infected abdominal wall defects in the elective setting.
Who can participate
Age range20 Years – 86 Years
SexALL
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Inclusion Criteria:
* Study group: patients with the presence of an active chronic mesh infection (non-healing sinus, exposed mesh, or mesh-related enteric fistulas) resulting from a previous repair, or the presence of an enteric/enteroatmospheric fistula, with or without an associated abdominal wall defect
* Control group: patients with a primary or recurrent ventral hernia without previous history of infection and eligible for clean operations
Exclusion Criteria:
* giant ventral hernias with a volume ratio higher than 25% and loss of domicile
* patients on immunosuppressive therapy or using corticosteroids
* patients with portal hypertension
* patients with Chron´s disease
* acute postoperative mesh infection
* chronic mesh infections following inguinal hernia repair
* emergency operations.