The first part of this study is to optimize diagnostic criteria for BMS, i.e. not a clinical trial, and will not be covered in this application. The second part will compare topical treatment with clonazepam, capsaicin and placebo in a n-of-1 study design regarding effects of pain, pain-related disability, somatosensory changes in the trigeminal nerve and patient experience in patients with primary BMS or other oral mucosal pain. The patients will be treated for two weeks with each drug, with a one-week wash-out period in between. After the last washed-out period, the patients will be able to chose the treatment that they prefer the most and continue with that treatment during 6 months.
Age range
30 Years – 80 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Pain intensity
Timeframe: Point measurement, will be assessed immediately before start of treatment
Pain intensity
Timeframe: Point measurement, will be assessed 10 days after treatment start for each treatment period.
Pain intensity
Timeframe: Point measurement, will be assessed the day after each treatment period is finished (22 days after start of each treatment)
Patient satisfaction
Timeframe: Point measurement, will be assessed immediately before start of treatment
Patient satisfaction
Timeframe: Point measurement, will be assessed 10 days after treatment start for each treatment period.
Patient satisfaction
Timeframe: Point measurement, will be assessed the day after each treatment period is finished (22 days after start of each treatment)