Clinical Study of Radiotherapy Combined With Nedaplatin Contrast and Cisplatin for the Treatment … (NCT05039606) | Clinical Trial Compass
Not Yet RecruitingPhase 2
Clinical Study of Radiotherapy Combined With Nedaplatin Contrast and Cisplatin for the Treatment of Locally Advanced Head and Neck Squamous Carcinoma
China164 participantsStarted 2021-09
Plain-language summary
This study was designed as a prospective, multicenter and randomized clinical study of radiotherapy combined with Nedaplatin contrast and cisplatin for local advanced head and neck squamous SCC, aiming to explore the efficacy, safety and long-term efficacy of this trial and control groups and provide some evidence for the selection of clinical treatment options.
Who can participate
Age range18 Years – 70 Years
SexALL
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Inclusion criteria
✓. voluntarily participated and signed the informed consent form in writing
✓. is 18-70 and gender unlimited
✓. histologically proved to be squamous cell carcinoma
✓. as AJCC(version 8): -A, ⅣB head and neck squamous carcinoma unable or denied surgery; \~ A, ⅣB squamous carcinoma of the head and neck with the following postoperative risk factors: positive or proximal resection, lymph node envelope invasion, nerve and vascular invasion, primary focal pT3 or T4, N2 or N3 lymph node lesions.
✓. card score ≥ 70
✓. survival is expected to be ≥ for 6 months
✓. fertility women should guarantee contraception during entering the study