Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue (NCT05035628) | Clinical Trial Compass
CompletedNot Applicable
Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
Canada40 participantsStarted 2021-09-15
Plain-language summary
The objective of this project is to assess the effects of a 2-month cardiopulmonary rehabilitation program on cardiorespiratory fitness in long COVID19 patients. Quality of life, functional capacity, functional respiratory capacity, inflammatory profile, coagulation markers, cognitive functions and brain O2 saturation will also be assessed before and after the exercise rehabilitation program.
Who can participate
Age range40 Years – 80 Years
SexALL
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Inclusion Criteria:
* Age between 40 and 80
* Individuals infected by the SARS-COV2 virus, with positive PCR diagnosis
* Still having breathlessness and fatigue at least 3 months after the diagnosis of COVID-19 or patients presenting an increase of 1 point (compared to before infection) on the Modified Medical Research Council scale.
* Able to perform a maximal cardiopulmonary stress test and exercise training program in accordance with current guidelines on cardiopulmonary rehabilitation.
* Able to read, understand and sign the information and consent form.
Exclusion Criteria:
* pulmonary embolism diagnosed by scintigraphy
* Absolute and relative contraindication to exercise stress test and / or exercise training
* Recent cardiovascular events (cardiac decompensation or angioplasty or cardiac surgery, less than 1 month; valvular disease requiring surgical correction, active myopericarditis, severe ventricular arrhythmias not stabilized under treatment).
* Kidney failure requiring dialysis
* heart failure (NYHA III or IV)
What they're measuring
1
Change in cardiorespiratory fitness
Timeframe: Baseline and post-intervention at 2 months