A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossifi… (NCT05019001) | Clinical Trial Compass
CompletedNot Applicable
A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
China100 participantsStarted 2018-03-01
Plain-language summary
The efficacy of laminoplasty and laminectomy with fusion for ossification of the posterior longitudinal ligament with high occupation rate in the cervical spine is not clear in the literature report so far. This study is designed to further research the difference in efficacy between the two surgical methods.
Who can participate
SexALL
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Inclusion Criteria:
* Patients diagnosed by clinical symptoms, physical examination, X-ray, CT, and MRI with a high occupation rate of ossification of the posterior longitudinal ligament in the cervical spine need and can be treated surgically after preoperative examination.
* CT axial soft tissue window determine that the occupation rate of one or more spinal canal segments in C2-7 is more than 60%.
* Sagittal CT show ossification of more than 3 segments of the posterior longitudinal ligament of the cervical spine.
* Sign the written informed consent
Exclusion Criteria:
* Participating in other interventional clinical trials;
* Mental disorders or cognitive disorders;
* Heart and lung diseases;
* Nervous system diseases;
* Patients with serious liver and kidney diseases, tumors and infectious diseases;
* There are any other factors that the treated doctors consider unsuitable for inclusion or completion of the study.
* Patients with cervical spondylotic radiculopathy
* Patients with severe osteoporosis, skeletal fluorosis and other reasons for which laminoplasty is not feasible
* Patients with ossification of posterior longitudinal ligament of cervical spine with invasion rate ≥60% had cervical trauma
* The patient with cervical ligamentum flavum ossification was diagnosed at the C2-7 level
* Preoperative pregnancy test was performed to exclude pregnant women