A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossifi… (NCT05019001) | Clinical Trial Compass
CompletedNot Applicable
A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
China100 participantsStarted 2018-03-01
Plain-language summary
The efficacy of laminoplasty and laminectomy with fusion for ossification of the posterior longitudinal ligament with high occupation rate in the cervical spine is not clear in the literature report so far. This study is designed to further research the difference in efficacy between the two surgical methods.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients diagnosed by clinical symptoms, physical examination, X-ray, CT, and MRI with a high occupation rate of ossification of the posterior longitudinal ligament in the cervical spine need and can be treated surgically after preoperative examination.
* CT axial soft tissue window determine that the occupation rate of one or more spinal canal segments in C2-7 is more than 60%.
* Sagittal CT show ossification of more than 3 segments of the posterior longitudinal ligament of the cervical spine.
* Sign the written informed consent
Exclusion Criteria:
* Participating in other interventional clinical trials;
* Mental disorders or cognitive disorders;
* Heart and lung diseases;
* Nervous system diseases;
* Patients with serious liver and kidney diseases, tumors and infectious diseases;
* There are any other factors that the treated doctors consider unsuitable for inclusion or completion of the study.
* Patients with cervical spondylotic radiculopathy
* Patients with severe osteoporosis, skeletal fluorosis and other reasons for which laminoplasty is not feasible
* Patients with ossification of posterior longitudinal ligament of cervical spine with invasion rate ≥60% had cervical trauma
* The patient with cervical ligamentum flavum ossification was diagnosed at the C2-7 level
* Preoperative pregnancy test was performed to exclude pregnant women
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.