RecruitingNot Applicable

Transmission Electron Microscopy Images for Platelet Ultrastructural Criteria Before and After the Onset of an Antiplatelet Agent

France50 participantsStarted 2024-12-13

Plain-language summary

The aim of the pilot study is to collect all the ultrastructural platelet characteristics by transmission electron microscopy before and after the onset of an antiplatelet treatment in patients hospitalized for an ischemic stroke ; and to assess recurrence of Ischemic Cerebral Accident (ICA) at 6 months in patients hospitalized for Ischemic stroke.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Social security affiliation * Signed informed consent * patients hospitalized for an non cardioembolic ischemic stroke requiring the onset of an antiplatelet therapy according to the usual guidelines recommendations Exclusion Criteria: Contraindications regarding antiplatelet agent(s) and/or at least one excipient according to Summary of Product Characteristics (SPC).

What they're measuring

Morphology of the platelet :

Timeframe: Day 5

Type of granules in the platelet

Timeframe: Day 5

Distribution of mitochondria, glycogen and dense tubular system in platelets

Timeframe: Day 5

Structure of open canalicular system in platelets

Timeframe: Day 5

Number of patients with a microtubular ring on the equatorial section plane (peripheral or centralized) in platelets

Timeframe: Day 5

Trial details

NCT IDNCT05004233

SponsorCentre Hospitalier Universitaire de Saint Etienne

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-06

Contact for this trial

PIERRE GARNIER, MD

(0)477127805 pierre.garnier@chu-st-etienne.fr

View on ClinicalTrials.gov More Ischemic Stroke trials