BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis

Inclusion Criteria: * Unilateral lower extremity DVT occlusion involving iliac and/or common femoral veins with up to 2 cm extension in the inferior vena cava (IVC) or femoral in combination with iliac veins, including patients with extension of clot into the contralateral common iliac vein Note: Patients with non-iliofemoral DVT in the contralateral limb, who do not require endovascular treatment, may be enrolled * Acute thrombotic or thromboembolic occlusion with symptom duration of 14 days or less at presentation * Frontline treatment with Indigo Aspiration System in the target venous segment per Investigator decision * Patient is ≥18 years of age * Informed consent is obtained per Institutional Review Board requirements Exclusion Criteria: * Contraindication to systemic or therapeutic doses of anticoagulants * Contraindication to iodinated contrast venography that cannot be adequately premedicated * Complete infrarenal IVC occlusion * In the index leg: prior DVT * Prior stent in target venous segment * Treatment of index DVT with thrombolytics within 14 days prior to index procedure * Pulmonary embolism (PE) defined as either high (systolic blood pressure \< 90 mmHg and/or patient on IV vasoactive medication to support blood pressure), or intermediate high-risk PE, as defined by the European Society Guideline on management of PE. Low risk PE and/or intermediate low risk PE can be enrolled. * Known coagulation disorders both acquired (e.g., Heparin Induced Thrombocytope…